Establishment of genome informatics infrastructure for human bioscience

Project Gist

Elucidate molecular mechanisms of human diseases by the comprehensive analysis of human phenotypes.

Keywords

Human diseases, genetic background, multiple omics study, life style and environment, preemptive medicine

Background, Purpose, and Project Achievements

An international joint research framework in the field of genomic medicine was successfully established with McGill University and Pasteur Institute. A model case of “Preemptive Medicine” enabling accurate diagnosis at a very early stage of disease and prognosis prediction was established through an approach of trans-ethnic multiomics analysis of human phenotypes together with whole genome analysis of a variety of diseases. Scientific meetings were organized in March 2014 and march 2015 at Kyoto University by researchers in this joint effort. Research progress was reported by Kyoto and McGill teams and future research plans were discussed. A practical training course for NGS data analysis followed by an international symposium in medical genomics was held on that occasion.

Future Prospects

Our aim is to establish a joint degree system to educate doctoral students in cooperation with top-ranking foreign research / educational institutions, to develop human resources with an international perspective, being able to participate in a leadership position in collaborative research with foreign countries. We will focus on training specialists in genomics to play an active leading role in the rapidly growing field of life big data analytics.

Figures

Lectures and practical sessions of the training course in the 3rd Kyoto Course and Symposium on Bioinformatics for NGS with Application in Human Genetics
Lectures and practical sessions of the training course in the 3rd Kyoto Course and Symposium on Bioinformatics for NGS with Application in Human Genetics
Symposium of the Second Kyoto Course and Symposium on Bioinformatics for NGS with Application in Human Genetics
Symposium of the Second Kyoto Course and Symposium on Bioinformatics for NGS with Application in Human Genetics
Symposium of the 3rd Kyoto Course and Symposium on Bioinformatics for NGS with Application in Human Genetics
Symposium of the 3rd Kyoto Course and Symposium on Bioinformatics for NGS with Application in Human Genetics

Principal Investigator

MATSUDA Fumihiko

・MATSUDA Fumihiko
・Center for Genomic Medicine
・Professor Fumihiko Matsuda obtained his Ph.D. from Kyoto University Graduate School of Medicine in 1990. After working at Kyoto University Graduate School of Medicine as an assistant professor, he joined Centre National de Genotypage in Paris in 1998 as the head of gene identification. In 2003, he obtained a double appointment as a Professor of Kyoto University Graduate School of Medicine. From 2007 to 2010, he served as the directeur de recherche of INSERM (U. 852) and since 2008 he has been a Director of the Center for Genomic Medicine. Through various positions he has engaged, he has consistently devoted himself to the research for the human disease genomics using genome-wide approach. His major research interests include integrated omics analysis of human multigenetic disorders and large-scale genome cohort study.
http://www.genome.med.kyoto-u.ac.jp/homepage
http://www.genome.med.kyoto-u.ac.jp/NgsCourse/